蘭州大學(xué)

閻文錦：副教授，碩士生導(dǎo)師，于1993年從山西平遙考入蘭州大學(xué)化學(xué)系就讀于應(yīng)用化學(xué)專業(yè)，在1997年6月本科畢業(yè)后進(jìn)入秦山第三核電有限公司工作。在秦山工作5年后，于2002年考入蘭州大學(xué)生命科學(xué)學(xué)院。主要從事含氮有機小分子化合物藥物化學(xué)及藥理學(xué)研究。
郵箱   yanwj@lzu.edu.cn

教育經(jīng)歷

1993.9 - 1997.6   蘭州大學(xué)應(yīng)用化學(xué), 學(xué)士
2002.9 - 2007.6   蘭州大學(xué)生物化學(xué)與分子生物學(xué)，博士

工作經(jīng)歷

2010-2012蘭州大學(xué)基礎(chǔ)醫(yī)學(xué)院講師
2012- 蘭州大學(xué)基礎(chǔ)醫(yī)學(xué)院受聘為副教授、碩士生導(dǎo)師

研究領(lǐng)域

不對稱催化，手性藥物合成及藥理學(xué)研究

主持的在研項目

1.中央高�；�本科研業(yè)務(wù)費“含α-CF3胺結(jié)構(gòu)單元的氨基酸的合成研究” （lzujbky-2013-168 ）， 2013.1-2014.6
2. 國家自然科學(xué)基金面上項目“3-烷氧羰基靛紅亞胺的合成及其在合成手性雙取代3-氨基氧化吲哚化合物方面的應(yīng)用 ” ( No. 21272108 ), 2013-2016

代表性論著:

1.Dong Wang1, Jinyan Liang1, Jingchao Feng, Kairong Wang, Quantao Sun, Long Zhao, Dan Li, Wenjin Yan*, Rui Wang*（The Quinine Thiourea-catalyzed Asymmetric Strecker Reaction: An Approach for the Synthesis of 3-Aminooxidoles）advanced Synthesis & Catalysis 2013,355:548-58. (SCI 二區(qū), IF 6.048）
2. Jingchao Feng, Wenjin Yan, Dong Wang, Peng Li, Quantao Sun， Rui Wang (The highly enantioselective addition of indoles and pyrroles to isatins-derived N-Boc ketimines catalyzed by chiral phosphoric acids) Chem. Commun.,  2012, 48, 8003.  (SCI二區(qū), IF 6.169）
3. Wenjin Yan, Dong Wang, Jingchao Feng, Peng Li, Rui Wang (The Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatin and Their Application in Enantioselective Transformations) Org . Lett.  2012, 14, 2512   (SCI二區(qū), IF 5.862）
4. Wenjin Yan; Dong Wang, Jingchao Feng, Peng Li, Rui Wang（Zinc-Mediated Diastereoselective Synthesis of 3-Amino Oxindoles by Addition of Methyl and Terminal Alkynes to N-tert-Butanesulfinyl Ketimines） J. Org. Chem. 2012,  2012, 77, 3311.  (SCI二區(qū), IF 4.45）.
5．Wenjin Yan, Peng Li, Jingchao Feng, Dong Wang, Xianxing Jiang,Shaoqun Zhu, and Rui Wang (Design and Synthesis of Tridentate Ligand Inspired by the Phenomenon of Self-assembly Catalysis and its Application in Asymmetric Alkynylation of N-(diphenylphosphinoyl) Imines) Tetrahedron: Asymmetry 2010, 2037-2042. (SCI三區(qū), IF 2.625）.
6．Shaoqun Zhu, Wenjin Yan, Bin Mao, Xianxing Jiang, Rui Wang. Enantioselective Nucleophilic Addition of Trimethylsilylacetylene to N-Phosphinoylimines Promoted by C2-Symmetric Proline–Derivatived β-Amino Alcohol. J. Org. Chem. 2009, 6980-6985. (SCI二區(qū), IF 4.45）
7．Wenjin Yan, Bin Mao, Shaoqun Zhu, Xianxing Jiang, Zhongli Liu, and Rui Wang. Asymmetric Addition of Terminal Alkynes to N-(diphenylphosphinoyl) Imines Promoted by Stoichiometric Amount Proline-Derived β-Amino Alcohol. Eur. J. Org. Chem. 2009, 3790-3794.
(SCI三區(qū), IF 3.20 )
8.  K Wang, J Yan, W Dang, X Liu, R Chen, J Zhang, B Zhang, W Zhang, M Kai, Wenjin Yan, Z Yang, J Xie, Rui Wang. Membrane active antimicrobial activity and molecular dynamics study of a novel cationic antimicrobial peptide polybia-MPI, from the venom of Polybia paulista. Peptides 2013, 39,80–88. （SCI三區(qū)，IF=2.421）