中國藥科大學(xué)藥學(xué)院研究生導(dǎo)師介紹：戴振亞

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情況簡介：

戴振亞，2000年在南京大學(xué)獲得學(xué)士學(xué)位，專業(yè)為化學(xué)，2005年10月在南京大學(xué)獲得博士學(xué)位，專業(yè)為有機(jī)化學(xué)，2005年11月至2007年8月在德國萊布尼茲催化研究所從事博士后研究，2007年8月至今在中國藥科大學(xué)擔(dān)任教師，并于2008年12月被聘為副教授。目前主持國家自然科學(xué)基金青年教師基金一項(xiàng)，參與江蘇省自然科學(xué)基金一項(xiàng)。目前發(fā)表論文23篇，其中SCI收錄16篇。聯(lián)系方式：daizhenya@hotmail.com，15951867995。

研究方向：不對稱催化，不對稱合成，手性藥物合成，藥物合成新方法研究。

發(fā)表論文目錄：

1.Jiangtao Sun, Chengjian Zhu*, Zhenya Dai, Minghua Yang, Yi Pan, Hongwen Hu. Efficient Asymmetric Oxidation of Sulfides and Kinetic Resolution of Sulfoxides Catalyzed by Vanadium Salan System. J. Org. Chem. 2004, 69, 8500-8503.
2.Zhenya Dai, Chengjian Zhu*, Minghua Yang, Yi Pan*. Asymmetric addition of organogallium to aldehydes catalyzed by chiral titanium catalyst. Tetrahedron: Asymmetry. 2005, 16，605－608.
3. Zhenya Dai, Chengjian Zhu*, Yi Pan*. Utilization of organogallium and organoindium compounds as alkylation reagents in organic synthesis: the addition of trialkylgallium and trialkylindium to aldehydes catalyzed by Lewis acids. Applied Organometallic Chemistry 2005, 7, 898-902.
4.Haibing Zhu, Zhenya Dai, Wei Huang, Kai Cui, Shaohua Gou*, Chenjian Zhu*. Chiral copper(II) complexes of optically active Schiff bases: syntheses, crystal structure and asymmetric oxidation of methyl phenyl sulfide with hydrogen peroxidePolyhedron 2004, 23, 1131-1137
5.Zhenya Dai, Detlef Heller, Anke Spannenberg, Hans-Joachim Drexler. Crystal structure of (η4-cycloocta-1,5-dien)-((+)-1,1'-bis((2R,4R)-2,4-diethyl-phosphotano)-ferrocene)-rhodium(I) tetrafluoroborate, [Rh(C8H12)Fe(C12H18FeP)2][BF4]  Z. Krist. (NCS) 2007, 222, 109.
6.Zhenya Dai, Detlef Heller, Angelika Preetz, Hans-Joachim Drexler. Crystal structure of (η4-cycloocta-1,5-dien)-N-(2-(diphenylphosphinooxy)-3-(naphthalen-1-yloxy)propyl)-N-(pentan-3-yl)-1,1-diphenylphosphinamine-rhodium(I)tetrafluoroborate, [Rh(C8H12)(C42H43NO2P2)][BF4] Z. Krist. (NCS) 2007, 222, 111.
7.Ralph Jackstell, Zhenya Dai, Thomas Schmidt, Detlef Heller, Hans-Joachim Drexler. Crystal structure of 1-(2-(dicyclohexylphosphinophenyl)pyrol-2-dicyclohexylphosphino-rhodium(I) norborna-2,5-diene tetrafluoroborate tetrahydrofuran hemisolvate, [Rh(C34H51NP2)(C7H8)][BF4] 0.5C4H8O, and 1-(2-(dicyclohexylphosphinophenyl)pyrol-2-dicyclohexylphosphino-rhodium(I) (Z,Z)-cycloocta-1,5-diene tetrafluoroborate, [Rh(C34H51NP2)(C8H12)][BF4] Z. Krist. (NCS) 2007, 222, 458.
8.Angelika Preetz, Hans-Joachim Drexler, Christian Fischer, Zhenya Dai, Armin Borner, Wolfgang Baumann, Anke Spannenberg, Richard Thede, Detlef Heller. Rhodium catalyst catalyzed asymmetric hydrogenation-Transfer of the precatalyst into active species. Chemistry: A European Journal 2008, 14, 1445.
9.Thomas Schmidt, Zhenya Dai, Hans-Joachim Drexler, Wolfgang Baumann, Christian Jäger, Dietmar Pfeifer, Detlef Heller*. Novel contributions to the mechanism of the enantioselective hydrogenation of dimethyl itaconate with rhodium complexes. Chemistry: A European Journal 2008, 14, 4469-4471.
10.Thomas Schmidt, Zhenya Dai, Hans-Joachim Drexler, Detlef Heller* The major/minor concept:dependence of the selectivity of homogeneously catalyzed reactions on the reactivity ratio and concerntration of the intermediates. Chemistry: An Asian Journal 2008, 1170-1180.
11.Jiangtao Sun, Zhenya Dai, Minghua Yang, Xu Pan, Chengjian Zhu* Vanadium-salan catalyzed enantioselective ring-opening of meso-epoxides with aromatic amines. Synthesis, 2008, 13, 2100-2104.
12.Jiangtao Sun*, Minghua Yang, Zhenya Dai, Chengjian Zhu*, Hongwen Hu Synthesis of Optically Active 2,5-Dialkylcyclohexane-1,4-diols and Their Application in the Asymmetric Oxidation of Sulfides. Synthesis, 2008, 13, 2513-2518.
13.Jiangtao Sun, Xu Pan, Zhenya Dai, Chengjian Zhu* Synthesis of new Schiff base-camphorsulfonyl amide ligands and in situ screening in asymmetric addition of organozinc reagents to aldehydes. Tetrahedron: Asymmetry 2008, 19, 2451-2457.
14.Jiangtao Sun, Zhenya Dai*, Changsi Li, Xu Pan, Chengjian Zhu* Enantionselective pinacol coupling reaction of aromatic aldehydes catalyzed by chiral vanadium catalyst. Jouranl of Organometallic Chemistry 2009, 3219-3221.
15.Thomas Schmidt, Hans-Joachim Drexler, Jiangtao Sun, Zhenya Dai, Wolfgang Baumann, Angelika Preetz, Detlef Heller* Unusual Deactivation in the Asymmetric Hydrogenation of Itaconic Acid. Advanced Synthesis & Catalysis 2009, 351(5), 750-754.
16.Xiaoyang Dong, Ziyu Wang, Daorui Huang, Pei Xu, Zhenya Dai*, Synthesis of New Chiral Phase Transfer Catalysts and their Application in the Asymmetric Alkylation of Glycine Derivatives. Austin Journal of Analytical and Pharmaceutical Chemistry. 2014, 1(1), 3-5.
17.Ziyu Wang, Daorui Huang, Pei Xu, Xiaoyang Dong, Xiaolong Wang and Zhenya Dai *The asymmetric alkylation reaction of glycine derivatives catalyzed by the novel chiral phase transfer catalysts Tetrahedron Lett. 2015, 56, 1067-1071.
18.Xiaoyang Dong, Pei Xu, Ziyu Wang, Daorui Huang, Zhenya Dai*. Asymmetric sulfenylation of glycine derivative catalyzed by the novel chiral phase transfer catalysts. Austin J Anal Pharm Chem. 2015, 2(1), 1032.
19.Ziyu Wang, Xueyan Zhang, Pei Xu, Daorui Huang, Xiaolong Wang, Zhenya Dai*. Research on phase transfer catalytic reactions and their application in drug synthesis. Austin J Anal Pharm Chem. 2015, 2(1), 1033.
20.Lin Qiu, Daorui Huang, Guangyang Xu, Zhenya Dai, Jiangtao Sun*. Realized C−H Functionalization of Aryldiazo Compouds via Rhodium Relay Catalysis. Org. Lett. 2015, 17, 1810-1813.
21.李長思，戴振亞*等地爾硫卓中間體的合成工藝改進(jìn)藥學(xué)與臨床研究2011,19,184-185.
22.王永超，戴振亞*等地爾硫卓中間體a,b-三元腈的合成藥學(xué)與臨床研究2011,19,470-471
23.劉洋，戴振亞*等氯沙坦合成工藝改造藥學(xué)與臨床研究2011,19,89-90
24.李長思，戴振亞*等脯氨酸催化的酮的不對稱a-硫代反應(yīng)藥學(xué)與臨床研究2010,18,243-246.
25.袁飛鵬，戴振亞*等脯氨酸催化的醛的不對稱a-硫代反應(yīng)藥學(xué)進(jìn)展2010,34,554-558.
26.盧協(xié)勤，戴振亞*等相轉(zhuǎn)移催化的甘氨酸叔丁酯衍生物的硫代反應(yīng)河北醫(yī)藥2012,34,1075-1077.
27.董曉陽，戴振亞*等不對稱小分子催化合成的最新進(jìn)展及其在藥物合成中的應(yīng)用中國藥科大學(xué)學(xué)報(bào)2013,44,193-201.

申報(bào)及授權(quán)專利目錄：

1.戴振亞，袁飛鵬等，羅本考昔的一種制備方法，專利授權(quán)號：CN102311355B.
2.戴振亞，袁飛鵬等，馬氟考昔的一種制備方法，專利號：201210063799.
3.戴振亞，王永超等，一種手性相轉(zhuǎn)移催化劑及其合成方法，專利號：201210085648.
4.戴振亞，王永超等，一種甘氨酸叔丁酯衍生物的不對稱烷基化方法，專利號：201210085610.
5.戴振亞，袁飛鵬等，R-4-芐氧吡咯烷的一種制備方法，專利號：201210085627.
6.王森，曹鑫，曹聰，戴振亞，陸愛軍，HDM2和HDMX雙重抑制劑3－腈基喹啉衍生物及其制備方法與應(yīng)用專利授權(quán)號：CN103804292A.
7.戴振亞，董曉陽等，一種新型手性相轉(zhuǎn)移催化劑的合成及其應(yīng)用，專利號：201410088280.6.
8.戴振亞，王子昱，黃道銳，徐沛一種環(huán)狀金雞納堿季銨鹽化合物的制法以及用途,專利號：201410455252.3.
9.王森，曹鑫，戴振亞，曹聰，張凌霄，(+)-生物素的制備方法，CN103833769A.
10.戴振亞，趙云德，王子昱，張學(xué)艷，許莎莎，依托考昔的一種合成方法，CN104693113A.