北京化工大學輕工技術與工程專業研究生導師介紹：羅施中

羅施中，教授，博士生導師。

1999年本科畢業于清華大學化學系，同年免試攻讀清華大學直博生，2004年獲清華大學化學博士學位，并榮獲清華大學優秀博士學位論文獎。2004年至2008年，在美國德克薩斯大學休斯頓醫學科學中心生物化學和分子生物學系從事博士后科研工作。2008年9月以北京化學大學高層次引進人才的方式進入北京化工大學生命學院工作，主要從事生物化工和化學生物學的相關研究工作，包括生物自組裝體系的研究；基于生物加工過程中的相關代謝調控、代謝組學和蛋白質組學研究；食品安全和環境安全檢測；計算化學和分子模擬研究。

作為項目負責人先后承擔國家自然科學基金項目，科技部863項目，北京市科技新星和教育部博士點基金項目，作為承擔單位的負責人承擔973重大研究計劃項目和國家自然科學基金重點項目各1項。發表了包括國外高水平期刊Blood，JBC，JMB和Biophysical Journal在內的SCI論文二十多篇，參編專著一本。榮獲2013年北京市科技新星，2013年北京市科學技術獎（三等獎），2012年北京化工大學第十二屆青年主講教師，2008年第十屆中國國際多肽大會Young Peptide Scientist Award等獎勵。

主要發表文章如下：

 

1)          Zhiling Zhu, Mengxue Feng, Limin Zuo, Zhentai Zhu, Fengwei Wang, Long Chen, Jinghua Lib, Guangzhi Shan*, Shi-Zhong Luo*(通訊作者)  An aptamer based surface plasmon resonance biosensor for the detection of2 ochratoxin A in wine and peanut oil. Biosensors and Bioelectronics Accepted (IF=6.0，Top雜志)；

2)          Fude Sun, Lei Zhang, Jianhua Yan, Lida Xu, Decai Fang and Shi-Zhong Luo*(通訊作者)  The synthesis and photolysis mechanisms of 8-nitroquinoline-based photolabile caging groups for carboxylic acid.  J. Phys. Org. Chem. Accepted (SCI)

3)          Peng Wei, Lida Xu,  Cheng-Dong Li, Fu-De Sun, Long Chen, Tianwei Tan, Shi-Zhong Luo*(通訊作者)  Molecular Dynamic Simulation of the Self-Assembly DAP12-NKG2C Activating Immunoreceptor Complex.  PLOS One, 9(8), e1005560 (IF=3.7，Top雜志)

4)          Peng Wei, Bo-Kai Zheng,Peng-Ru Guo, Toru Kawakami, Shi-Zhong Luo*(通訊作者) The Association of Polar Residues in the DAP12 homodimer: TOXCAT and Molecular Dynamics Simulation Studies Biophysical Journal, 2013 Apr 2;104(7):1435-44. (IF=4.3，Top雜志)；

5)          Yunfei Sun, Long Chen, Fude Sun, Xibo Tian, Shi-Zhong Luo* New amphiphilic N-phosphoryl oligopeptides designed for gene delivery. International Journal of Pharmaceutics 468 (2014) 83–90 (IF=3.6)；

6)          Lin Chang，Pengyu Bi，Yanan Liu，Yinglin Mu，Fengquan Nie，Shizhong Luo， and Yun Wei*, Simultaneous Analysis of Trace Polymer Additives in Plastic Beverage Packaging by Solvent Sublation Followed by High-Performance Liquid Chromatography J. Agric. Food Chem. dx.doi.org/10.1021/jf401748a (IF=2.9，Top雜志)

7)          Lida Xu  Ting-Ting Hu Shi-Zhong Luo*(通訊作者) Leucine Zipper Motif Drives the Transmembrane Domain Dimerization of E-cadherin International Journal of Peptide Research and Therapeutics, Accepted. (SCI)

8)          Fengxiang Qie, Guoxin Zhang, Jianxuan Hou, Xiaoming Sun, Shi-zhong Luo*(通訊作者), Tianwei Tan* Nucleic acid from beans extracted by ethanediamine magnetic particles Journal of Food Science and Technology (SCI)

9)          Xi-Rui Zhou, Rui, Ge, Shi-Zhong Luo* (通訊作者) Self-assembly of pH and calcium dual-responsive peptide-amphiphilic hydrogel. Journal of Peptide Science. 2013 19(12): 737-44. (IF=1.8)

10)       Xiao-Li Lv, Shi-Zhong Luo*(通訊作者) A fluorescence chemosensor based on peptidase for detecting  nickel(II) with high selectivity and high sensitivity, Analytical and Bioanalytical Chemistry, 2012, 402(9):2999-3002; (IF=3.84，二區雜志)；

11)       Fengxiang Qie, Guoxin Zhang, Jianxuan Hou, Xiaoming Sun, Shi-Zhong Luo*(通訊作者), Tianwei Tan*(通訊作者), Talanta, 2012, 93,166-171; (IF=3.7，二區雜志)；

12)       Xiao-Li Lv, Yun Wei, Shi-Zhong Luo*(通訊作者) A “Turn-On” Fluorescent Chemosensor Based on Peptidase for Detecting Copper (II), Analytical Science,2012, 28(8), 749. (SCI) 獲得當期的Hot Article Award

13)       Peng Wei, Xin Liu, Miaohui Hu, Limin Zuo, Rui Wang, Shi-Zhong Luo*（通訊作者）The dimerization interface of the glycoprotein Ibb transmembrane domain corresponds to polar residues within a leucine zipper motif, Protein Science, 2011,20(11):1814-1823; (IF=3.0, 二區雜志)；

14)       Ting-Ting Hu and Shi-Zhong Luo*，“Phosphorylation-Induced Structural Changes in the C-Terminus of c-Fos Detected by CD and NMR” International Journal of Peptide Research and Therapeutics, 2011,17(1):19-30. (SCI)

15)       Yan-Jing Kang, Li-Min Zuo, Shi-Zhong Luo*, “Hydrogen-Bonding Interactions Induced by Phosphorylation Influence the Local Conformation of Phosphopeptides”, International Journal of Peptide Research and Therapeutics, 2010，16(2):87-93. (SCI)

16)       Xi Mo, Nam X. Nguyen, Fi-tjen Mu, Shi-Zhong Luo, Huizhou Fan, Robert K. Andrews, Michael C. Berndt, Renhao Li. “Trans-membrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ib[alpha]”. Journal of Biology Chemistry, 2010, 285: 32096-32104. (IF=5.3，Top雜志)

17)       Shi-Zhong Luo, Renhao Li. “Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complex”, Journal of Molecular Biology, 2008, 382, 448-457. (IF=4.9，Top雜志)

18)       Shi-Zhong Luo, Xi Mo, Vahid Afshar-Kharghan, Sankaranarayanan Srinivasan José A.López, and Renhao Li. “Glycoprotein Ib? forms disulfides with two glycoprotein Ib? subunits in the resting platelet”. Blood, 2007, 109, 603-609. (IF=10.1，Top雜志) Featured in a commentary in Blood, 2007, 109, 393-394.

19)       Shi-Zhong Luo, Xi Mo, José A.López, and Renhao Li. “Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib-IX complex”. Journal of Thrombosis and Haemostasis, 2007, 5,2494-2502. (IF=5.9，二區雜志)

20)       Xi Mo, Shi-Zhong Luo, Yuandong Peng, Adam D Munday, Carol Sun, Michael C. Berndt, José A. López, Jing-fei Dong, and Renhao Li. “Removing the covalent links between GPIba and GPIbb hampers binding of von Willebrand Factor to GPIb-IX Complex in CHO cells”, Accepted by Journal of Thrombosis and Haemostasis. (IF=5.9，二區雜志)

21)       Xi Mo, Shi-Zhong Luo, José A. López, and Renhao Li. “Juxtamembrane basic residues in glycoprotein Ibb cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex”, FEBS Letters, 2008, 582, 3270-3274. (IF=3.4)

22)       Shi-Zhong Luo, Yan-Mei Li,.Wei Qiang, Yu-Fen Zhao, Hiroshi Abe, Tadashi Nemoto, Xu-Rong Qin, and Hiroshi Nakanishi. “Detection of Specific Non-Covalent Interaction of Peptide with DNA by MALDI-TOF”. Journal of The American Society for Mass Spectrometry, 2004,15,28-31(IF=3.6).

23)       Shi-Zhong Luo, Yan-Mei Li, Yan-Ling Niu, Yi Chen, Yu-Yang Jiang, Jing Chen and Yu-Fen Zhao. “Characterization of an Electrospray Ionization Mass Spectrometry for N-Diisopropyloxyphosphory Dipeptide Methyl Esters”. European Journal of Mass Spectrometry, 2005,11,107-118, (SCI)

24)  Shi-Zhong Luo, Yan-Mei Li, Zhong-Zhou Chen, Hiroshi Abe, Li-Ping Cui, Hiroshi Nakanishi, Xu-Rong Qin and Yu-Fen Zhao. “Synthesis and matrix assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry study of phosphopeptide”. Letters in peptide science, 2003,10,57-62. (SCI)