蘭州大學基礎醫學院導師介紹：白德成

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姓   名：白德成
Name： Bai Decheng
職 務：教授
Duty：  Professor
E-mail：bdc@lzu.edu.cn

一、 科研方向

1、腦細胞損傷與血粘度增高的相關性研究
2、腦外傷與血腦屏障開放的實驗研究
在研項目
1、腦紅蛋白對慢性進行性腦缺血缺氧的保護作用研究 甘肅省自然科學基金 2.0萬
2、慢性進行性腦缺血缺氧與腦紅蛋白表達的相關性研究 蘭州大學醫學基金 0.7萬
3、阿司匹林腦保護作用的實驗研究 甘肅省新藥臨床前研究重點實驗室創新基金 2.0萬元
ResearchInterests：
1、The correlation study of injury of brain cells and high blood viscosity.
2.、The experimental study of brain trauma and blood brain barrier opening.
Reserching project：
1. Protective effect of neuroglobin on chronic anoxia- Ischemic change of the brain
2、The correlation between expression of neuroglobin and anoxia- Ischemic change of the brain
3、The experimental research of brain protection of Aspirin
 
二、榮譽稱號及獎勵

榮譽稱號：甘肅省高等學校跨世紀學科帶頭人
獎      勵：
1、 貓皮質-后索核-脊髓通路的實驗形態學研究 甘肅省衛生廳科技成果獎 二等1985.07
2、胚胎脊髓組織移植修復脊髓損傷實驗研究 甘肅省衛生廳科技進步獎 三等  1993.06
3、手部神經損傷修復的實驗與臨床研究 甘肅省科委科技進步獎 三等  1996.04.
4、外科手術學實驗教學方法探索 甘肅省政府教學成果獎 二等1997.05  
5、大鼠嗅結節與腦干某些核團間的聯系 甘肅省衛生廳科技進步獎 三等  1997.08
6、教學、科研、生產為一體的實驗動物學教學探索 甘肅省政府教學成果獎 二等1999.12
7、 皮質-腦干核-脊髓系統和皮質-腦干核-小腦系統的形態學研究 甘肅省教育廳科技進步獎 二等2000.12
8、皮質-腦干-脊髓系統的形態學研究 甘肅省科技進步獎 二等2001.4
9、葡萄籽中原花青素對阿霉素增效減毒作用及機理研究 甘肅省科技進步獎 二等 2007.05
honors and awards：
honors:cross-century academic leader in Colleges and Universities of Gansu Province
awards:
1、An experimental study on the organization of cortico dorsofuniculo-spinal pathway in the cat. The second prize of Scientific Research Achievements by Health Department of Gansu Province,1985.07
2、Renovation of rat spinal cord injury by transplantation of rat embryo spinal cord tissue .The third prize of scientific and technological advance Achievements by Health Department of Gansu Province,1993.06
3、The experimental and clinical research therapeutic effect on neural injury in the hand.The third prize of scientific and technological advance Achievements by Science Committee of Gansu Province,1996.04
4、The research of the course of operative surgery and the way of experimental teaching.The second prize of teaching research in Gansu Province,1997.05
5、Connections between the olfactory tubercle and some of brainstem nuclei in rat.The third prize of scientific and technological advance Achievements by Health Department of Gansu Province,1997.08
6、The teaching exploration of scientific research, teaching and production combining in  laboratory animal science.The second prize of teaching research in Gansu Province,1999.12
7、Morphological study of cortical-brainstem nuclei-spinal system and cortical-brainstem nuclei- cerebellum system. The second prize of scientific and technological advance Achievements by Education Department of Gansu Province,1997.08
8、Morphological study of cortical-brainstem-spinal system.The second prize of scientific and technological advance Achievements by Gansu Province, 2001.04
9、Synergy and attenuation of doxorubicin activities by proanthocyanidins from grape seeds The second prize of scientific and technological advance Achievements by Gansu Province, 2007.05

三、個人簡歷

1974年?1977年   原蘭州醫學院醫療系醫療專業。
1981年?1984年   原蘭州醫學院神經解剖學專業  碩士研究生。
1977年?1989年   原蘭州醫學院解剖教研室任助教、講師。
1990年?2004年   原蘭州醫學院外科手術學教研室任講師、副教授，設備處副處長、國資處處長，教學科研儀器報損報廢鑒定專家組成員。
2005年?2007年   蘭州大學臨床醫學院外科手術學教研室任教授，實驗室與設備管理處處長，教學科研儀器報損報廢鑒定專家組成員。
2007年?至    今   蘭州大學基礎醫學院外科手術學教研室任教授，實驗室與設備管理處處長，教學科研儀器報損報廢鑒定專家組成員。
Resume（including education background， English）：
1974至1977   Medical departments medical majors, Lanzhou Medical College。
1978至1984   Neuroanatomical majors,Lanzhou Medical College  Postgraduate。
1977至1989   Department of Anatomy, Lanzhou Medical College  Assistant and Instructor。
1990至2004   Department of Operative Surgery, Lanzhou Medical College  Instructor and Associate Professor, Deputy Director of the Equipment Department, Division Chief of State-owned Property Administration, Member of Identification Specialists in reported as loss and discard of Teaching and Scientific Instruments and Facilities。
2005至2007   Department of Operative Surgery of Clinical Medical College Lanzhou University     Professor, Division Chief of Laboratory and  Equipment Management Department, Member of Identification Specialists in reported as loss and discard of Teaching and Scientific Instruments and Facilities。
2007 until now   Department of Operative Surgery of Basic Medical College Lanzhou University  Professor, Division Chief of Laboratory and  Equipment Management Department, Member of Identification Specialists in reported as loss and discard of Teaching and Scientific Instruments and Facilities。

四、發表論文

1984   大腦皮質向三叉神經脊束尾側亞核的投射
1985   大腦皮質向后索核投射的試驗形態學研究
1985   皮質-后索核-脊髓通路的形態學研究
1985   皮質-后索核-脊髓通路的研究現狀和簡史
1986   中縫核族向嗅前核的投射
1987   臂旁核向大腦皮質的投射
1987   臂旁核-嗅球傳入纖維的又一來源
1988   貓Darkschewisch`s核向大腦皮質的投射
1988   腦干神經元向小腦絨球和脊髓的分支投射
1988   The projections of the cerebellar nuclei to the cerebellar cortex and the spinal cord
1990   大鼠視神經傳出纖維的HRP法結合熒光追逐法研究
1992   皮質-巨細胞網狀核-脊髓通路--HRP結合潰變電鏡法研究
1992   局解手術學協作教學的可行性和必要性
1993   單側胸鎖乳突肌缺如一例的巨微觀察
1994   局解、手術學協作教學初探
1995   恒河猴皮質脊髓束與脊髓神經元的突觸聯系
1995   大鼠大腦皮質-下橄欖-小腦通路中的突觸復合體
1995   大鼠后根-楔外側核-小腦傳入通路的HRP潰變電鏡法研究
1996   SD大鼠皮質小腦前核纖維終扣的電鏡觀察
1996   蘭州醫學院SPF小鼠飼育設施的設計與建設
1997   大鼠大腦皮質投向小腦前核纖維的超微結構和突觸聯系
1997   小鼠25s神經生長因子對大鼠、小鼠受損坐骨神經再生的影響
1997   局解、手術學協作教學效果分析
1997   皮質-PMRN-小腦通路--HRP結合潰變電鏡法研究
1997   大鼠PMRN中皮質纖維終末的超微結構觀察
1997   大鼠大腦皮質-外側網狀核-小腦通路
1998   皮質-網狀-脊髓通路─HRP法結合潰變電鏡法研究
1998   皮質腦干纖維終末的超微結構 潰變電鏡法研究
1999   大腦皮質-小腦前核-小腦通路-- HRP結合潰變電鏡法研究
1999   大白鼠小腦前核中皮質纖維與小腦投射神經元間的突觸聯系
2003   實驗性高粘血癥對腦組織丙二醛和超氧化物歧化酶含量的影響
2003   Arsenic trioxide inhibits P-glycoprotein expression of multidrug-resistant human leukemia ells that overexpress mdr-1 gene and induces apoptosis
2003   Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide
2004   高血粘度對小鼠腦細胞內游離鈣濃度及腦組織丙二醛含量的影響
2004   小鼠腦細胞內游離鈣濃度與高血粘度致腦血管病的相關性
2005   高血粘度大鼠血液有形成分及血液流變性的動態觀察
2005   Proanthocyanidi from grape seeds enhances doxorubicin- induced antitumor effect and rveres drug resistance in doxorubicin-resistant K562/DOX cells
2005   Proanthocyanidin from grape seeds enhances anti-tumor effect of doxorubicin both in vitro and in vivo
2008   外源性鋅對缺氧神經元的保護作用
2008   化學性缺氧致大鼠腦細胞[Ca2+]i和腦紅蛋白表達變化及阿司匹林干預研究

五、學術團隊

趙秉江（教師）   程   菊（教師）  趙麗霞（學生）